Methyltrienolone is a steroid compound.
The advantage of the drug in the oral release form is its convenient use
Metribolone allows the following effects on the bodybuilder’s body:
muscle growth up to 8 kg capacity
removal of joints, ligaments and muscle pain
proliferation of red blood cells
improving blood oxygenation
Estrogenic side effects:
Methyltrienolone does not aromatize and has no estrogenic activity. Dimethyltrienolone has an affinity for progesterone receptors. This can cause side effects of progesterone, such as a stop in the production of testosterone and an increase in body fat. Progestogens also increase the stimulatory effect of estrogen on breast tissue growth. The synergy is so strong that gynecomastia can be caused by progestins alone without an increase in estrogen levels. The use of antiestrogens may alleviate progestin-AAS-induced gynecomastia.
Androgenic side effects:
Methyltrienolone is classified as anabolic, but androgenic side effects are highly possible. Growth of oily skin, acne, body and facial hair can be increased. Anabolic steroids can worsen hair loss in men. Women should also be aware of the potential virilizing effects of ASA. This may include a deeper voice, irregular periods, changes in the structure of the skin, growth of facial hair, and an enlarged clitoris. Methyltrienolone does not react with 5α-reductase and its androgenicity cannot be altered by concomitant use of finasteride or dutasteride.
Side effects (hepatotoxicity):
Methyltrienolone is a c17-alpha-alkylated drug. This modification protects the drug from liver inactivation, allowing a greater percentage of the drug to enter the bloodstream when ingested orally. Alkylated ASA can be hepatotoxic. Prolonged use or high doses may cause liver damage. In rare cases, life-threatening disorders may develop. During the course, it is recommended to see a doctor regularly to monitor liver function. Intake of alkylated ASA is generally limited to 6-8 weeks to avoid additional hepatic stress. Methyltrienolone is a highly potent oral steroid and has high resistance to hepatic metabolism. This makes it very toxic to the liver, which is why it has never been sold in pharmacies. This was demonstrated in a 1966 study published at the University of Bonn, Germany. In fact, the researchers concluded that it was the most toxic drug to the liver: “Methyltrienolone … is an oral drug that is active in less than 1 milligram per day and has been shown to affect liver function. Measurements were made with several parameters: sulfobromole retention, total bilirubin, transaminase alkaline phosphatase, blood cholinesterase, plasma proacelin activity Based on the results on the effect on hepatic cholestasis, methyltrienolone is the most hepatotoxic drug.
The use of liver cleansing supplements such as Liver Stabil, Liv-52 and Essentiale Forte may be recommended during the course.
Side effects (cardiovascular system):
ASA can have a detrimental effect on blood cholesterol. This may be a decrease in “good” HDL levels, a change in balance toward the risk of atherosclerosis. The relative effect of ASA on lipids depends on dose, route of administration, steroid type, and level of resistance to hepatic metabolism. Methyltrienolone has a stronger negative effect on the regulation of hepatic cholesterol due to its non-aromatic structure and route of administration. ASA can negatively affect blood pressure and triglycerides, reduce vascular endothelial relaxation, cause ventricular hypertrophy, which may increase the risk of cardiovascular disease and heart attack. To reduce the burden on the cardiovascular system, it is recommended to minimize the intake of saturated fats, cholesterol, and simple carbohydrates during AAS therapy. The use of supplements such as fish oil, lipid stabilizers or similar products is recommended.